CISH Antikörper (AA 17-130)

Produktnummer ABIN7266663

Dieser Anti-CISH Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CISH in WB und IF. Geeignet für Human.

Kurzübersicht für CISH Antikörper (AA 17-130) (ABIN7266663)

Target: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CISH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CISH Antikörper

Bindungsspezifität: AA 17-130

Verwendungszweck: CISH Rabbit pAb

Sequenz: TGQRPLWAPS LELPKPVMQP LPAGAFLEEV AEGTPAQTES EPKVLDPEED LLCIAKTFSY LRESGWYWGS ITASEARQHL QKMPEGTFLV RDSTHPSYLF TLSVKTTRGP TNVR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CISH

Target: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Andere Bezeichnung: CISH

Hintergrund: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.,CISH,BACTS2,CIS,CIS-1,G18,SOCS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,CISH

Molekulargewicht: 28kDa/29kDa/30kDa

Gen-ID: 1154

UniProt: Q9NSE2

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus